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Abstract #1450

Regional variations in cerebral venous contrast using susceptibility-based MRI

Phillip G. D. Ward1,2, Nicholas J. Ferris1,3, Parnesh Raniga1,4, Amanda C. L. Ng5, David L. Dowe2, David G. Barnes2,6, and Gary F. Egan1,7

1Monash Biomedical Imaging, Monash University, Clayton, Australia, 2Faculty of Information Technology, Monash University, Clayton, Australia, 3Monash Imaging, Monash Health, Clayton, Australia, 4The Australian eHealth Research Centre, CSIRO Health and Biosecurity, Australia, 5Department of Anatomy and Neuroscience, The University of Melbourne, Melbourne, Australia, 6Monash Immersive Visualisation Platform, Monash University, Clayton, Australia, 7ARC Centre of Excellence for Integrative Brain Function, Melbourne, Australia

In this study we compared the image contrast properties of susceptibility-weighted imaging (SWI) and quantitative susceptibility mapping (QSM) for cerebral venous identification and visualisation. SWI and QSM are minimally invasive techniques to image cerebral veins with distinct contrast properties. We hypothesised that these techniques would provide complementary vein contrast in different brain regions. Contrast was measured using 1072 manually traced vein images from ten volunteers. We found regional variations in the predictive power of vein contrast and computed maps of contrast profiles that may inform which technique is best for a given application.

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