Abstract #1451

Quantitative and qualitative evaluation of bias field correction methods

Falk Luesebrink¹, Hendrik Mattern¹, Alessandro Sciarra¹, and Oliver Speck^1,2,3,4

¹Biomedical Magnetic Resonance, Otto-von-Guericke University, Magdeburg, Germany, ²Center for Behavioral Brain Sciences, Magdeburg, Germany, ³Leibniz Institute for Neurobiology, Magdeburg, Germany, ⁴German Center for Neurodegenerative Disease (DZNE), Magdeburg, Germany

Bias field correction is an essential prerequisite for image analysis, especially at high field strength. In this study multiple correction methods, based on acquisition of a reference image and computational approaches with varied input parameters, are compared. The results indicate that acquisition of a conventional MPRAGE corrected by SPM yields quantitatively and qualitatively comparable results to acquiring a reference image (e.g. MP2RAGE), however, scan time is up to halfed.

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