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Abstract #1493

An algorithm for refocusing of T2* effects in bSSFP-MRF with relaxation corrections

Mingdong Fan1, Danielle Kara1, Jesse I. Hamilton2, Nicole Seiberlich2,3, Mark Griswold2,3, and Robert Brown1

1Physics, Case Western Reserve University, Cleveland, OH, United States, 2Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, 3Radiology, University Hospitals Case Medical Center, Cleveland, OH, United States

It is found that bSSFP-MRF is in general subject to T2* not T2 relaxation. Like traditional bSSFP, dephasing effects of intra-voxel inhomogeneities can be refocused in bSSFP-MRF with appropriate choices in TR, TE, and FA so that parameter maps are reflective of T2 rather than T2*. An algorithm is introduced and verified in simulation for refocusing intra-voxel dephasing at TE for bSSFP-MRF with corrections to previous work for relaxation effects previously assumed as negligible. These corrections are relevant for bSSFP-MRF in which T2 is not much larger than TR to ensure that T2 maps do not contain T2* effects.

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