Quantitative blood oxygenation level dependent (qBOLD) technique provides an invaluable and noninvasive means for mapping brain oxygen extraction fraction (OEF) and R2’ in various neurological disorders. However, background magnetic field inhomogeneity causes errors in the measurement. In this work, we propose a triple echo asymmetric spin echo sequence with imbedded Z-shimming table to measure and correct the adversary effect of the field inhomogeneity. With both simulation and 16 patient image sets, we have demonstrated the effectiveness of the proposed technique.
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