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Abstract #1540

Comparative T2 and T1ρ Mapping of Patellofemoral Cartilage under in situ Mechanical Loading with Prospective Motion Correction

Thomas Lange1, Benjamin R. Knowles1, Michael Herbst1,2, Kaywan Izadpanah3, and Maxim Zaitsev1

1Department of Radiology, Medical Physics, Medical Center - University of Freiburg, Freiburg, Germany, 2John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, United States, 3Department of Orthopedic and Trauma Surgery, Medical Center - University of Freiburg, Freiburg, Germany

Robust comparative T2 and T mapping of patellofemoral cartilage under in situ loading is demonstrated with prospective motion correction and T2 and T changes in response to loading are evaluated quantitatively, focusing on the load-bearing lateral patellar facet. T2 and T mapping were performed with equal spatial resolution and field of view for different loading conditions (0/20/40 kg). While no significant T2 differences for the three loading conditions were observed, T in superficial patellar cartilage was significantly reduced under loading. The quantitative findings suggest that T is a more reliable and sensitive marker for load-induced changes than T2.

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