Abstract #1547

Biomechanical T2-mapping in osteoarthritis with 3D-TESS at 7T MRI

Sebastian Roehrich¹, Pavol Szomolanyi¹, Markus Schreiner², Vladimir Juras¹, Rahel Heule³, Oliver Bieri³, and Siegfried Trattnig^1,4

¹Department of Biomedical Imaging and Image-guided Therapy, High Field MR Centre, Medical University of Vienna, Vienna, Austria, ²Department of Orthopedic Surgery, Medical University of Vienna, Vienna, Austria, ³Department of Radiology, Division of Radiological Physics, University of Basel Hospital, Basel, Switzerland, ⁴Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria

Biochemical MRI of hyaline cartilage shows promising results for the evaluation of OA. In this study we implemented in-vivo compression and a fast 3D-TESS sequence at 7T for cartilage transversal relaxation time (T2)-mapping of healthy volunteers and patients with risk factors for the development of early osteoarthritis of the knee (OA). Results show a location-dependent and differing behavior of T2-values under compression between the two groups, further increasing the value of T2-values as possible biomarker for OA.

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