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Abstract #1557

Compressed Sensing Microscopic MRI in Articular Cartilage at 7T: Quantitative Determination of GAG Concentration using dGEMRIC Method

Nian Wang1, Farid Badar2, and Yang Xia2

1Center for In Vivo Microscopy, Department of Radiology, Duke University, Durham, NC, United States, 2Physics and Center for Biomedical Research, Oakland University, Rochester, MI, United States

To evaluate the compressed sensing feasibility of quantification GAG concentration using dGEMRIC method, high resolution T1 mapping of articular cartilage was accelerated using various acceleration factors. It demonstrates that using CS doesn’t introduce major deviations in quantification of GAG concentration even with acceleration factor of 16, which holds great promise in making quantitative imaging techniques more accessible for clinical applications.

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