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Abstract #1563

Quantitative Evaluation of T2 Signal Intensity for the Assessment of Muscle Denervation

Parina H. Shah1, Erin C. Argentieri1, Matthew F. Koff1, and Darryl B. Sneag1

1Radiology and Imaging, Hospital for Special Surgery, New York, NY, United States

Presence and severity of muscle denervation due to peripheral neuropathy are conventionally evaluated using needle electromyography (EMG); the results of which are critical in the diagnosis of nerve injury and prognosticating nerve recovery. Routine MRI can confirm the presence of denervation but is unable to quantify severity and relies on qualitative detection of diffuse T2-weighted signal hyperintensity of the muscle and fatty infiltration (if chronic). This pilot study explores the role of T2 mapping in the diagnosis denervation and for quantification of severity. T2 mapping may be an important complement to EMG results, particularly given the drawbacks associated with EMG.

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