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Abstract #1574

Multicomponent 3D-T1ρ and T2 Relaxation Mapping of Skeletal Muscle: In-vivo Feasibility

Azadeh Sharafi1, Gregory Chang 1, and Ravinder Regatte1

1Radiology, New York University, School of Medicine, New York, NY, United States

In this study, we investigated the in-vivo feasibility of multicomponent 3D-T1ρ and T2 relaxation mapping in calf muscle using 3T MRI in clinically feasible scan times on eight healthy volunteers. Our preliminary results demonstrate that the biexponential model better characterized the relaxation behavior in calf muscle and can be used to differentiate between different water compartments associated with macromolecules (collagen and contractile proteins) and extracellular/vascular water in calf muscle.

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