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Abstract #1590

Potential of High Resolution Isotropic Microstructural MRI of the Proximal Femur

Austin G. Alecxih1, Elizabeth A. Kobe2, Alyssa J. Johncola2, Marissa L. Evans2, Shivali Patel2, Sun M. Kim2, Benjamin T. Newman2, Gregory Chang3, Christian McHugh2, and Chamith S. Rajapakse2

1University of Pennsylvania, Philadelphia, PA, United States, 2University of Pennsylvania, 3New York University

Microstructural MRI based finite element modelling is an area of current research in regards to the role that this technology can play as an efficient and affordable metric for quantifying bone integrity and for identifying fracture risk. This study was conducted in an attempt to unveil the extent to which MRI resolution impacts the quantitative output generated by finite element models pertaining to the parameter of bone stiffness of the proximal femur in vitro. Conclusions reveal a statistically significant variance relative to the values generated for two differing MRI resolution classes.

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