Abstract #1591

Simplified approach to quantification for hand synovitis in rheumatoid arthritis using dynamic contrast enhanced MRI: pixel-by-pixel time intensity curve shape analysis

Yuto Kobayashi¹, Tamotsu Kamishima², Taro Sakashita³, Hiroyuki Sugimori², Shota Ichikawa¹, Atsushi Noguchi⁴, Michihito Kono⁴, Toshitake Iiyama⁵, and Tatsuya Atsumi⁴

¹Graduate School of Health Sciences, Hokkaido University, Sapporo, Japan, ²Faculty of Health Sciences, Hokkaido University, Sapporo, Japan, ³National Sale Division, CT Sales Department, Application Group, Toshiba Medical Systems Corporation, Tochigi, Japan, ⁴Internal Medicine 2, Hokkaido University Hospital, Sapporo, Japan, ⁵Yaesu Clinic, Tokyo, Japan

Quantification for synovitis using time intensity curve (TIC) shape analysis of rheumatoid arthritis has been believed to require long acquisition time up to 6-7 minutes to observe washout phase. In this study, we found that wash out phase does not contribute to accurate depiction of synovitis in the hand and simplified TIC shape analysis could significantly decrease acquisition time from about 6 minutes to 3 minutes.

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