Abstract #1598

Perfusion and Fat Content of Lumbar Vertebral Body: Global and Regional Analysis

Hou-Ting Yang^1,2, Yi-Jui Liu³, Hing-Chiu Chang⁴, Xiang-Wei Xie⁵, Ming-Fun Lin⁵, and Wing P. Chan^5,6

¹Department of Nuclear Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ²Program of Electrical and Communications Engineering, Feng Chia University, Taichung, Taiwan, ³Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan, ⁴Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, ⁵Department of Radiology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan, ⁶Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taiwan

Vertebral blood perfusion has been reported that there was a decrease trend in normal aging people and post-menopause women and those with arteriosclerosis, fat marrow increased and osteoporosis. Although DCE-MRI and MRS have shown potential probing bone marrow content and blood perfusion characteristics of vertebra body in previous studies, all of these were ROI analysis only and lack regional information for bone marrow content and blood perfusion. Therefore, The purposes of this study were to investigate the regional perfusion and bone marrow content in vertebra body with use of DCE-MRI and six-point Dixon IDEAL technique by pixel-by-pixel analysis.

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