The aim of this study was to explore the fat fraction(FF) variation of inter and intra vertebral bodies in the lumbar spine, by using water-fat imaging. In lumbar spine, L1 and L2 vertebras demonstrated lower FF level but with more common ‘margin higher’ FF distribution pattern comparing to other vertebras, which might be related to stress and activities of the vertebra. We suggested that FF distribution pattern indicate certain skeletal remodeling that affects bone strength, which may be a promising indicator in assessing prevalent fracture besides the increased average FF of the whole vertebral body.
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