Embolization following percutaneous intervention is a universal problem occurring in all vascular beds, especially in lower extremities. This study assesses the performance of a noninvasive MRI based oxygenation imaging, in characterizing muscle oxygen extraction fraction (OEF) level after microsphere-induced lower extremity embolization in animal models. By comparison of the calculated muscle OEFs and R2’ before and after surgery, significantly increase could be found. The results show promise in the evaluation of early muscle ischemia in many clinical diseases such as acute lower limb embolism or peripheral artery disease.
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