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Abstract #1623

Isotropic High Spatial Resolution fMRI Using Accelerated Variable Density Spiral and SLIDER

Xuesong Li1, Xiaodong Ma1, Lyu Li1,2, Yan Tong3, Sen Song4, and Hua Guo1

1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, People's Republic of China, 2Philips Healthcare, Shanghai, People's Republic of China, 3FMRIB Centre, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, United Kingdom, 4Department of Biomedical Engineering, School of Medicine, Tsinghua University, People's Republic of China

fMRI with high spatial resolution is beneficial for studies in psychology and neuroscience, but is limited by various factors such as prolonged imaging time and low signal-to-noise ratio. In this work, we combined Dual-TRACER method with SLIDER technique to obtain up to 1mm isotropic fMRI image, while maintaining temporal resolution comparable with conventional acquisition. Using the proposed method, finger somatotopy maps were successfully located on a 3T scanner.

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