Abstract #1623

Isotropic High Spatial Resolution fMRI Using Accelerated Variable Density Spiral and SLIDER

Xuesong Li¹, Xiaodong Ma¹, Lyu Li^1,2, Yan Tong³, Sen Song⁴, and Hua Guo¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, People's Republic of China, ²Philips Healthcare, Shanghai, People's Republic of China, ³FMRIB Centre, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, United Kingdom, ⁴Department of Biomedical Engineering, School of Medicine, Tsinghua University, People's Republic of China

fMRI with high spatial resolution is beneficial for studies in psychology and neuroscience, but is limited by various factors such as prolonged imaging time and low signal-to-noise ratio. In this work, we combined Dual-TRACER method with SLIDER technique to obtain up to 1mm isotropic fMRI image, while maintaining temporal resolution comparable with conventional acquisition. Using the proposed method, finger somatotopy maps were successfully located on a 3T scanner.

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