Abstract #1752

Population averaged ferret brain templates for in-vivo and ex-vivo anatomical and diffusion tensor MRI

Elizabeth B Hutchinson^1,2,3, Susan Schwerin^3,4, Kryslaine Radomski⁴, Neda Sadeghi^1,2, Michal Komlosh^2,3, Jeffrey Jenkins^1,2,3, Okan Irfanoglu^1,2,3, Sharon Juliano⁴, and Carlo Pierpaoli^1,2

¹Quantitative Medical Imaging Section, NIBIB, NIH, Bethesda, MD, United States, ²SQITS/NICHD, NIH, Bethesda, MD, United States, ³Henry M. Jackson Foundation, Bethesda, MD, United States, ⁴APG, Uniformed Services University of the Health Sciences, Bethesda, MD, United States

In-vivo and Ex-vivo anatomical MRI and DTI templates were generated for the ferret brain along with region of interest segmentation masks based on known ferret neuroanatomy. Templates were built from multiple ferret brain images for each modality using advanced template building tools including symmetric normalization transformation for structural templates and Diffeomorphic Registration for Tensor Accurate AlignMent of Anatomical Structures (DRTAMAS) for DTI templates. The resulting templates are made available on an interactive web site (mriferretatlas.nichd.nih.gov).

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