Bi-exponential diffusion model is widely used to fit for non-Gaussian diffusion. T2 relaxation rates differ between structural compartments, which may bias the results of fits to microstructure models. We incorporate T2 relaxation into the bi-exponential model and leveraged the Gmax = 300mT/m gradient strength of the Connectome scanner to study the apparent T2 times of the two diffusion components. A longer T2 was found for the fast diffusion component when the model allows for different T2 times, but both multiple T2s and single T2 models seem to fit to the data fairly well. The added T2 parameter affects volume fraction more than diffusivity estimates.
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