Abstract #1756

MR imaging of the cervical spinal cord in patients with spinal muscular atrophy and healthy controls

Wieke Haakma^1,2, Marloes Stam³, Martijn Froeling¹, Marielle E.P. Philippens⁴, Clemens Bos¹, Alexander Leemans⁵, Ludo van der Pol³, and Jeroen Hendrikse¹

¹Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands, ²Department of Forensic Medicine and Comparative Medicine Lab, Aarhus University, Aarhus, Denmark, ³Department of Neurology, University Medical Center Utrecht, Utrecht, Netherlands, ⁴Department of Radiotherapy, Cancer Center, University Medical Center Utrecht, Utrecht, Netherlands, ⁵Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands

We studied the architecture and diffusion characteristics in the cervical spine and nerves in spinal muscular atrophic (SMA) patients and healthy controls. We showed the asymmetrical architectural configuration of the cervical nerves in SMA patients. We computed diffusion values of which the mean, axial, and radial diffusivity were lower in the SMA patients than in healthy controls which are in accordance with the clinical symptoms of these patients. Diffusion values of the cervical spine (grey, white and the whole myelum) showed no differences.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.