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Abstract #1781

Toward Analytic Computation of Fiber-Radial Diffusional Kurtosis by Q-space Data Representation with Radial Basis Functions

Yoshitaka Masutani1 and Koh Sasaki1,2

1Graduate School of Information Sciences, Hiroshima City University, Hiroshima, Japan, 2Hiroshima Heiwa Clinic, Hiroshima, Japan

To enhance the robustness of the fiber-radial diffusional kurtosis computation, the signal decay in the Q-space can be averaged among the fiber-radial orientations. By using the radial basis functions with Gaussian basis, it is shown that the fiber-radial signal decay can be represented in a pseudo-analytic form with the Bessel function. By using in-vivo diffusion MRI data, the computation results were presented in comparison with those by diffusion kurtosis tensor of 4th order to prove the effectiveness of the proposed method.

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