The performance of diffusion kurtosis imaging (DKI) in the analysis of micro-structural changes of brain tissue affected by acute ischemic stroke was explored. 199 lesions in common affected locations were divided into six groups. The value of DKI-derived indices and their changed percentage relative to normal contralateral ROI were calculated. Multiple comparisons among groups indicated that kurtosis indices (especially MK and Ka) showed better performance compared to diffusion indices (ADC, MD, Da and Dr) in detecting structure changes of brain tissues affected by acute ischemic stroke.
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