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Abstract #1821

Value of the Intravoxel Incoherent Motion MRI in Pretreatment Predicting and Monitoring the Early Response to Chemoradiotherapy in Esophageal Squamous Cell Carcinoma

fei ping li1, zhongping zhang2, and Xiaoping Yu1

1Hunan Cancer Hospital, Changsha, People's Republic of China, 2MR Research China, GE Healthcare, Beijing, People's Republic of China

Chemoradiotherapy (CRT) was considered to be a very effective treatment regimen for locally advanced or unresectable esophageal cancer (EC). Usually the therapy-induced early changes of tumor microenvironment were prior to morphological changes, which cannot be detected by traditional imaging techniques. This study used intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) to investigate the early response to CRT in esophageal squamous cell carcinoma (ESCC). It was found that the IVIM-DWI parameters (ADC and D) might be valuable in pretreatment predicting and monitoring the early treatment response to CRT in ESCC.

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