Abstract #1822

Rectal Adenocarcinoma: Diagnostic Accuracy of Diffusion Kurtosis Imaging (DKI) and its Correlation with Prognostic Factors

Lan Zhu¹, Xu Yan², Cai xia Fu³, Huan Zhang¹, Zilai Pan¹, and Fuhua Yan¹

¹Radiology, Ruijin Hosptial, Jiaotong University, Shanghai, People's Republic of China, ²MR Collaboration NE Asia, Siemens Healthcare, Shanghai, People's Republic of China, ³APPL, Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, People's Republic of China

The high resolution MRI and conventional DWI suffers from unsatisfying accuracy in assessment of some prognostic factors of rectal adenocarcinoma. We employed DKI, a protocol mainly for evaluating the complexity of biologic tissues, to explore its diagnostic accuracy and correlation with prognostic factors. The kurtosis of DKI exhibited highest correlation with histologic grades especially the new grading criterion and higher potential in differentiation of high- and low grade tumors, and also in predicting nodal status, with higher specificity than or equivalent sensitivity to diffusivity and ADC. In conclusion, DKI could be a promising tool in predicting prognosis of rectal adenocarcinoma.

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