Intravoxel incoherent motion diffusion weighted imaging was conducted on different radio-sensitive human NPC xenografts (CNE-1 and CNE-2) in order to investigate its application value in assessing the pathological features and tumor’s hypoxia of xenografts. CNE-2 xenografts of higher radio-sensitivity behaved greater changes on IVIM-parameters than CNE-1 xenografts of lower radio-sensitivity after fractional radiations. D and f values correlated significantly with the pathological features and tumor’s hypoxia of xenografts. Thus, IVIM-parameters is potentially valuable in evaluating the effect of radiotherapy in NPC.
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