Abstract #1832

High-resolution diffusion imaging of post-mortem monkey brain: comparison of 3D Spin Echo and 3D segmented EPI sequence at 11.7T

Sophie Bernadette Sébille^1,2, Anne-Sophie Rolland², Carine Karachi^2,3, Marie-Laure Welter^2,4, Eric Bardinet^1,2, and Mathieu David Santin^1,2

¹Center of NeuroImaging Research - CENIR, Paris, France, ²Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, Paris, France, ³AP-HP, Hôpital de la Pitié-Salpêtrière, Department of Neurosurgery, Paris, France, ⁴AP-HP, Hôpital de la Pitié-Salpêtrière, Department of Neurology, Paris, France

Diffusion-weighted spin echo (SE) acquisition is the golden-standard of diffusion imaging, yet it is limited by a very long acquisition time. This work present the optimization of a 3D segmented Echo Planar Imaging (EPI) sequence with the goal of reducing acquisition time and be able to perform tractography and to promote further analysis such as microstructure or histology correlation.

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