Meeting Banner
Abstract #1833

Comparaison of in vivo and ex vivo high resolution imaging of the mouse brain at 11.7T

Sophie Bernadette Sébille1,2, Isaac Adanyeguh1,2, Elise Marsan2, Sirenia Lizbeth Mondragon-Gonzalez2,3, Fatma Gargouri1,2, and Mathieu David Santin1,2

1Center of NeuroImaging Research - CENIR, Paris, France, 2Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, Paris, France, 3Behavior, Emotion and Basal Ganglia (BEBG), Brain and Spine Institute, Paris, France

This study compares high resolution in vivo and ex vivo diffusion imaging of mouse brain at 11.7T. The study shows that even with the advancement in image sequences and equipment, ex vivo imaging remains superior to in vivo imaging in terms of resolution with clear delineation of brain structures. However, fractional anisotropy values obtained from ex vivo imaging may not be a true representation of the in vivo condition. Nonetheless, the resolution obtained from in vivo imaging should allow for longitudinal studies.

This abstract and the presentation materials are available to members only; a login is required.

Join Here