Abstract #1841

High Resolution Cardiac DTI - Fiber Tractography Statistics of the ex Vivo pig Heart

David Lohr¹, Maxim Terekhov¹, Andreas Max Weng², Anja Schroeder^3,4, Heike Walles^3,4, and Laura Maria Schreiber¹

¹Comprehensive Heart Failure Center, University Hospital Wuerzburg, Wuerzburg, Germany, ²Department of Diagnostic and Interventional Radiology, University Hospital of Wuerzburg, Wuerzburg, Germany, ³Department Tissue Engineering and Regenerative Medicine, University Hospital Wuerzburg, Wuerzburg, Germany, ⁴Translational Center Wuerzburg 'Regenerative therapies', Wuerzburg branch of the Fraunhofer IGB, Wuerzburg, Germany

A whole heart, high resolution diffusion tensor data set with 1.3 mm isotropic voxels was acquired in 15 ex vivo pig hearts using a Stejskal-Tanner sequence at 3T. ADC, FA and HA values were calculated and analyzed for the whole heart. Purpose was to create a reliable statistical reference of diffusion parameters. Sharp modes for median and interquartile range of the ADC and median and mean values of the helix angle indicate similar distributions of those values for the individual hearts. This provides a statistically compelling reference for future cardiac DTI pig studies in vivo and at higher field strengths.

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