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Abstract #1858

Diffusion Tensor Imaging of human muscle at ultra-high-field (7T) MR.

Chiara Giraudo1, Stanislav Motyka1, Christoph Resinger2, Thorsten Feiweier3, Siegfried Trattnig1, and Wolfgang Bogner1

1Department of Biomedical Imaging and Image-guided Therapy- MR Centre of Excellence, Medical University of Vienna, Vienna, Austria, 2Orthopedic Department, Evangelisches Krankenhaus Wien, Vienna, Austria, 3Siemens Healthcare GmbH, Erlangen, Germany

Ultra-high-field (7T) imaging already demonstrated to provide more robust DTI measurements in comparison to 1.5 and 3T in the brain but, to the best of our knowledge, it was not applied for DTI measurements on human muscles. Our results showed higher SNR as well as an overall improvement in DTI metrics for the entire calf muscle at 7T than at 3T. Single muscle analyses (gastrocnemii, tibialis anterior) demonstrated more heterogeneous results. Future studies including a larger population and considering technical challenges (e.g.,RF inhomogeneity, gradient performance) are necessary to assess if 7T may provide higher benefits in specific muscles.

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