Abstract #1858

Diffusion Tensor Imaging of human muscle at ultra-high-field (7T) MR.

Chiara Giraudo¹, Stanislav Motyka¹, Christoph Resinger², Thorsten Feiweier³, Siegfried Trattnig¹, and Wolfgang Bogner¹

¹Department of Biomedical Imaging and Image-guided Therapy- MR Centre of Excellence, Medical University of Vienna, Vienna, Austria, ²Orthopedic Department, Evangelisches Krankenhaus Wien, Vienna, Austria, ³Siemens Healthcare GmbH, Erlangen, Germany

Ultra-high-field (7T) imaging already demonstrated to provide more robust DTI measurements in comparison to 1.5 and 3T in the brain but, to the best of our knowledge, it was not applied for DTI measurements on human muscles. Our results showed higher SNR as well as an overall improvement in DTI metrics for the entire calf muscle at 7T than at 3T. Single muscle analyses (gastrocnemii, tibialis anterior) demonstrated more heterogeneous results. Future studies including a larger population and considering technical challenges (e.g.,RF inhomogeneity, gradient performance) are necessary to assess if 7T may provide higher benefits in specific muscles.

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