Abstract #1870

Targeted-FOV DWI can better depict the microemboli-induced renal lesions comparing to conventional full-FOV DWI

Chengyan Wang¹, Li Jiang², Hanjing Kong¹, Fei Gao³, Wenjian Huang¹, Rui Wang⁴, Lian Ding¹, Yan Jia⁵, Hui Xu⁵, He Wang⁶, Xiaodong Zhang⁴, Li Yang⁵, Jue Zhang^1,3, Xiaoying Wang^1,4, and Jing Fang^1,3

¹Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, People's Republic of China, ²Philips Healthcare, Suzhou, People's Republic of China, ³College of Engineering, Peking University, Beijing, People's Republic of China, ⁴Department of Radiology, Peking University First Hospital, Beijing, People's Republic of China, ⁵Renal Division, Peking University First Hospital, Beijing, People's Republic of China, ⁶Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, People's Republic of China

DWI suffers from problems of severe geometric distortion and artifacts due to the susceptibility gradients and long echo train length (ETL), and the spatial resolution is quite limited due to the single-shot EPI acquisition scheme. This study investigates the utility of a targeted-FOV (TFOV) DWI technique in characterizing acute renal injure caused by microemboli injection in animal models. Compared with full-FOV DWI, the TFOV DW images show apparently higher image quality and better depiction of renal lesions. The advantage of TFOV DWI technique in characterizing microemboli-induced acute renal injure in is quite obvious.

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