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Abstract #1889

Measurement of lung perfusion using optimized pseudo-continuous arterial spin labeling of pulmonary arteries and fast True-FISP imaging at 3 Tesla

Petros Martirosian1, Rolf Pohmann2, Martin Schwartz1,3, Thomas Küstner3,4, Wolfhard Binder5, Christina Schraml4, Ferdinand Seith4, Nina Schwenzer4, Klaus Scheffler2,6, Konstantin Nikolaou4, and Fritz Schick1

1Section on Experimental Radiology, University of Tübingen, Tübingen, Germany, 2Max Planck Institute for Biological Cybernetics, Tübingen, Germany, 3Institute of Signal Processing and System Theory, University of Stuttgart, Stuttgart, Germany, 4Department of Diagnostic and Interventional Radiology, University of Tübingen, Tübingen, Germany, 5Department of Paediatric Cardiology, University of Tübingen, Tübingen, Germany, 6Department of Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany

Pseudo-continuous-arterial-spin-labeling (pCASL) has been successfully applied in the brain and kidney providing high signal-to-noise-ratio. The aim of this study was to optimize pCASL for measurement of lung perfusion by optimized labeling of pulmonary arteries and fast signal acquisition. Effective labeling of pulmonary arteries was possible by ECG triggering and an appropriate orientation of the labeling plane. Sufficient signal from lung parenchyma was acquired by True-FISP imaging with TE=1ms. The presented method provides high quality perfusion images of the lung without applying intravenous contrast agents and offers diagnostic imaging of lung diseases such as pulmonary embolism and bronchial carcinoma.

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