Abstract #1889

Measurement of lung perfusion using optimized pseudo-continuous arterial spin labeling of pulmonary arteries and fast True-FISP imaging at 3 Tesla

Petros Martirosian¹, Rolf Pohmann², Martin Schwartz^1,3, Thomas Küstner^3,4, Wolfhard Binder⁵, Christina Schraml⁴, Ferdinand Seith⁴, Nina Schwenzer⁴, Klaus Scheffler^2,6, Konstantin Nikolaou⁴, and Fritz Schick¹

¹Section on Experimental Radiology, University of Tübingen, Tübingen, Germany, ²Max Planck Institute for Biological Cybernetics, Tübingen, Germany, ³Institute of Signal Processing and System Theory, University of Stuttgart, Stuttgart, Germany, ⁴Department of Diagnostic and Interventional Radiology, University of Tübingen, Tübingen, Germany, ⁵Department of Paediatric Cardiology, University of Tübingen, Tübingen, Germany, ⁶Department of Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany

Pseudo-continuous-arterial-spin-labeling (pCASL) has been successfully applied in the brain and kidney providing high signal-to-noise-ratio. The aim of this study was to optimize pCASL for measurement of lung perfusion by optimized labeling of pulmonary arteries and fast signal acquisition. Effective labeling of pulmonary arteries was possible by ECG triggering and an appropriate orientation of the labeling plane. Sufficient signal from lung parenchyma was acquired by True-FISP imaging with TE=1ms. The presented method provides high quality perfusion images of the lung without applying intravenous contrast agents and offers diagnostic imaging of lung diseases such as pulmonary embolism and bronchial carcinoma.

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