Abstract #1890

Quantification of mouse renal perfusion using arterial spin labeled MRI at 1 Tesla

Quyen N. Do¹, Ananth J. Madhuranthakam^1,2, Peter Bendel³, and Robert E. Lenkinski^1,2

¹Radiology, University of Texas Southwestern Medical Center, Dallas, TX, United States, ²Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States, ³Aspect Imaging, Shoham, Israel

The current work demonstrates the use of a 1 Tesla desktop MR system to study mouse kidney perfusion through arterial spin labeling (ASL) technique. The validity of the implementation was tested by (1) comparing obtained perfusion results with literature values for normal mice and (2) challenging the technique with mice treated with a blood vessel vasoconstrictor drug. Potential applications include easy assessments of disease state, metabolism, and tissue perfusion using a compact MR system.

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