Abstract #1915

Absolute Quantification of Brain Perfusion using Golden Angle Compressed Sensing DCE-MRI

Radovan Jiřík¹, Marie Daňková², Pavel Rajmic², Lucie Krátká¹, Lenka Dvořáková¹, Eva Dražanová¹, and Zenon Starčuk, jr.¹

¹Institute of Scientific Instruments of the CAS, Brno, Czech Republic, ²Department of Telecommunications, Brno University of Technology, Brno, Czech Republic

A DCE-MRI method for absolute quantification of cerebral blood flow (CBF) and volume (CBV) and vessel permeability surface area product is presented. It is based on L+S compressed sensing, the two-compartment exchange model (2CXM) and blind deconvolution estimation of the arterial input function. The method is evaluated on data from a healthy rat.

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