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Abstract #1915

Absolute Quantification of Brain Perfusion using Golden Angle Compressed Sensing DCE-MRI

Radovan Jiřík1, Marie Daňková2, Pavel Rajmic2, Lucie Krátká1, Lenka Dvořáková1, Eva Dražanová1, and Zenon Starčuk, jr.1

1Institute of Scientific Instruments of the CAS, Brno, Czech Republic, 2Department of Telecommunications, Brno University of Technology, Brno, Czech Republic

A DCE-MRI method for absolute quantification of cerebral blood flow (CBF) and volume (CBV) and vessel permeability surface area product is presented. It is based on L+S compressed sensing, the two-compartment exchange model (2CXM) and blind deconvolution estimation of the arterial input function. The method is evaluated on data from a healthy rat.

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