Abstract #1924

Accurate Tissue Oxygen Level-dependent MRI with true T1-weighted signal

SoHyun Han¹, HyungJoon Cho², and Seong-Gi Kim^1,3

¹Center for Neuroscience Imaging Research, Institute for Basic Science (IBS), Suwon, Korea, Republic of, ²Department of Biomedical Engineering, Ulsan National Institute of Science and Technology, Ulsan, Korea, Republic of, ³Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of

Tissue oxygen level dependent (TOLD) MRI utilizes that T₁ is directly related with tissue pO₂. TOLD MRI is acquired by gradient echo based with a minimized TE. However, T₂^* contribution may not fully be suppressed. Here, we investigated the modulations of longitudinal and transverse relaxation times with oxygen challenge (OC) and compared TOLD signals from FLASH, UTE, and TSE at 7 T and 15.2 T. At both magnetic fields, T₂ did not change with tissue pO₂ while T₁ did. Spin echo and UTE appear to reflect true pO₂ levels due to invariability in T₂ during OC and minimized T₂^* with ultrashort TE, respectively.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.