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Abstract #1923

Feasibility of using Active Contrast Encoding (ACE)-MRI for Assessment of Tumor Treatment Response

Jin Zhang1, Willis Chen1, Kerryanne Winters1, and Sungheon Gene Kim1

1Center for Advanced Imaging Innovation and Research (CAI2R), Dept. Radiology, NYU School of Medicine, New York, NY, United States

Active Contrast Encoding MRI (ACE-MRI) is a recently proposed method to conduct DCE-MRI experiment without the need to perform separate T1 and B1 measurement. The purpose of this study is to further investigate the feasibility of using the ACE-MRI method for evaluation of tumor treatment response in a mouse model of breast cancer. The results of the ACE-MRI method were compared with conventional DCE-MRI data analysis with separately measured T1 maps. Our preliminary results demonstrate that the ACE-MRI method can be used to evaluate tumor treatment response reliably.

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