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Abstract #1933

Development and Systematic Analysis of 2D and 3D GRE Myelin Water Imaging

Hyeonggeol Shin1, Se-Hong Oh2, and Jongho Lee1

1Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of, 2Biomedical Engineering, Hankuk University of Foreign Studies, Seoul, Korea, Republic of

In this study, we developed high quality GRE-MWI methods for 2D and 3D acquisitions and performed systematic analysis on TR and flip angle. The myelin water images showed that image quality was higher in 2D than in 3D. Over a range of TR (56 ms to 1630 ms), the myelin water fraction was uniform when Ernst angles (assume T1 of 800 ms) were used. The fractions were overestimated when larger flip angles were used.

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