Abstract #1936

Measurement of T1, T2, and flip angle with double-angle inversion-recovery balanced steady state free precession with application to imaging the eye

Eric R. Muir¹ and Shengwen Deng^2,3

¹Research Imaging Institute and Ophthalmology, University of Texas Health Science Center, San Antonio, TX, United States, ²Research Imaging Institute, University of Texas Health Science Center, San Antonio, TX, United States, ³Biomedical Engineering, University of Texas at San Antonio, San Antonio, TX, United States

Fast measurement of T1 and T2 can be made with high signal to noise using inversion-recovery Look-Locker (LL) bSSFP. However, the LL-bSSFP signal is dependent on the flip angle, which must be known for accurate T₁ and T₂ calculation. In this study we investigated methods to additionally map and correct for the flip angle with the acquisition of two LL-bSSFP scans with two different flip angles, avoiding the need for a separate flip angle mapping protocol. Simulations and scans of the eye showed that T₁, T₂, and the flip angle could be measured with the double-angle LL-bSSFP method.

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