Abstract #1935

Spatial distribution of myelin concentration in healthy volunteers measured in GRE myelin water imaging, ViSTa myelin water imaging, quantitative MT and DTI

Dongmyung Shin¹, Sehong Oh², and Jongho Lee¹

¹Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of, ²Department of Biomedical Engineering, Hankuk University of Foreign Studies, Yongin, Korea, Republic of

This study investigated the spatial distribution of several myelin imaging methods. Myelin water fraction in GRE-MWI, apparent MWF in ViSTa-MWI, fractional pool size (F) in qMT, MT saturation, MT ratio, and FA in DTI were compared for their spatial distribution in white matter. Strong correlations were measured particularly between GRE-MWI and ViSTa-MWI and also among MT contrasts. FA showed least correlations with the other parameters.

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