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Abstract #1935

Spatial distribution of myelin concentration in healthy volunteers measured in GRE myelin water imaging, ViSTa myelin water imaging, quantitative MT and DTI

Dongmyung Shin1, Sehong Oh2, and Jongho Lee1

1Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of, 2Department of Biomedical Engineering, Hankuk University of Foreign Studies, Yongin, Korea, Republic of

This study investigated the spatial distribution of several myelin imaging methods. Myelin water fraction in GRE-MWI, apparent MWF in ViSTa-MWI, fractional pool size (F) in qMT, MT saturation, MT ratio, and FA in DTI were compared for their spatial distribution in white matter. Strong correlations were measured particularly between GRE-MWI and ViSTa-MWI and also among MT contrasts. FA showed least correlations with the other parameters.

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