Abstract #1960

Evaluation of Quantitative Susceptibility Mapping for the visualization of the Globus Pallidus Internus and Subthalamic Nucleus at 3T and 7T

Fei Cong^1,2, Zhangyan Yang^1,2, Xiaohong Joe Zhou³, Bo Wang¹, Yan Zhuo¹, and Lirong Yan⁴

¹State Key Laboratory of Brain and Cognitive Science, Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, People's Republic of China, ²Graduate University, Chinese Academy of Sciences, Beijing, People's Republic of China, ³Center for Magnetic Resonance Research, University of Illinois at Chicago, Chicago, IL, United States, ⁴Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, United States

The globus pallidus internus (GPi) and subthalamic nucleus (STN) (Figure 1) were the commonly used nuclei in deep brain stimulation (DBS) for the treatment of the Parkinson disease. In this study, we evaluated the QSM, T2* weighted and SWI methods for the visualization the GPi and STN on both 3T and 7T scanners. Our results showed the QSM at 7T displayed an excellent delineation of the GPi and STN, compared with T2* and SWI images.

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