Abstract #1959

Effects of Spatial Resolution on Quantitative Susceptibility Mapping

Timothy J Colgan^1,2, Samir D Sharma¹, Diego Hernando^1,2, and Scott B Reeder^1,2,3,4,5

¹Radiology, University of Wisconsin, Madison, WI, United States, ²Medical Physics, University of Wisconsin, Madison, WI, United States, ³Biomedical Engineering, University of Wisconsin, Madison, WI, United States, ⁴Medicine, University of Wisconsin, Madison, United States, ⁵Emergency Medicine, University of Wisconsin, Madison, WI, United States

The purpose of this study was to investigate the effects of spatial resolution on the performance of quantitative susceptibility mapping (QSM). The combination of magnitude contrast in spoiled gradient echo images and the voxel sensitivity function can create significant errors in the estimated B₀ field map. This work evaluated the use of proton density weighted imaging and joint R₂* and field map estimation to reduce the impact of imaging resolution on QSM. Our results indicate that reducing magnitude contrast in the complex-valued echo images will reduce errors in the field map estimates and, thus, the susceptibility estimates in QSM.

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