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Abstract #2005

The predictive value of diffusion-weighted imaging on radiation-induced liver injury of hepatic malignancies

Xiaohong Ma1, Shuang Wang1, Yongjian Zhu1, Han Ouyang1, Chunwu Zhou1, and Xinming Zhao1

1Diagnostic Radiology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, People's Republic of China

Radiation-induced liver injury (RILI) is one of the most dreaded complications of radiation therapy (RT)´╝îwhich prevents radiation dose escalation and limits the effectiveness of the treatment . Therefore, it was important to predict and evaluate the RILI on hepatic malignancy using the RT in the early term. In this study, the ADCmid-RT value was significantly highest, and had negative correlation with the radiation dose. As the ADCmid-RT value was less than 1.29 x10-3mm2/s, the RILI could possibly occur. Therefore, the ADCmid-RT value may serve as a biomarker for predicting RILI in patients with hepatic malignancies treated with RT.

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