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Abstract #2028

The effects of a 2 week hyperenergetic high carbohydrate or high fat diet on subcutaneous, visceral fat and metabolism

Mehri kaviani 1, Carolyn Chee2, Caroline Hoad1, Stephen Bawden1,3, Peter Mansell2, Sally Cordon2, Aithal Guruprasad3, Ian Macdonald2, and Penny Gowland1

1Sir Peter Mansfield Imaging Centre,Physics and Astronomy, Nottingham University, Nottingham, United Kingdom, 2School of Life Sciences, Nottingham University, Nottingham, United Kingdom, 3NIHR Nottingham Digestive Diseases Biomedical Research Unit, Nottingham University Hospitals NHS Trust and University of Nottingham

With the rise in obesity globally, there is great interest in quantifying body composition and in particular metabolically active visceral adipose tissue (VAT). Increased accumulation of VAT has been linked with an increase in risk factors for cerebrovascular disease and Type 2 Diabetes (T2DM) . We investigated the degree to which weight, subcutaneous fat visceral fat, liver and lipid markers are affected by 2 weeks of overfeeding at 25% excess energy given as either carbohydrate or fat. 2 weeks of 25% excess energy overfeeding of either carbohydrate of fat does not alter subcutaneous or visceral abdominal fat in line with no changes in weight. MRI measurements of SAT and VAT can be used in longitudinal studies of diet to ascertain any changes in abdominal body fat deposition.

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