Abstract #2030

Diffusion-Weighted Imaging and Variable Flip Angle T1 Mapping in Progression Assessment of Liver Fibrosis Caused by Hepatitis B Virus Infection: A longitudinal study

Peng Hu¹, Jihong Sun, Fangfang Lv, Borui Pi, Fangping Xu, Guocan Han, Xi Hu, Yue Wang, Ning Huang, Xia Wu, Yong Zhang, Jun Yang, Peipei Pang, and Xiaoming Yang

¹Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China

Liver fibrosis caused by Hepatitis B virus (HBV) is a worldwide health problem. However, liver biopsy as the gold standard of diagnosing and evaluating therapy of liver fibrosis is an invasive examination with possible errors from sampling and intra- and inter-observer interpretation (1, 2). The non-invasive MRI may be a promising modality to evaluate the liver fibrosis. We used diffusion-weighted imaging (DWI) and variable flip angle (VFA) T1 mapping to explore the progression of liver fibrosis caused by HBV infection in a longitudinal study.

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