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Abstract #2030

Diffusion-Weighted Imaging and Variable Flip Angle T1 Mapping in Progression Assessment of Liver Fibrosis Caused by Hepatitis B Virus Infection: A longitudinal study

Peng Hu1, Jihong Sun, Fangfang Lv, Borui Pi, Fangping Xu, Guocan Han, Xi Hu, Yue Wang, Ning Huang, Xia Wu, Yong Zhang, Jun Yang, Peipei Pang, and Xiaoming Yang

1Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China

Liver fibrosis caused by Hepatitis B virus (HBV) is a worldwide health problem. However, liver biopsy as the gold standard of diagnosing and evaluating therapy of liver fibrosis is an invasive examination with possible errors from sampling and intra- and inter-observer interpretation (1, 2). The non-invasive MRI may be a promising modality to evaluate the liver fibrosis. We used diffusion-weighted imaging (DWI) and variable flip angle (VFA) T1 mapping to explore the progression of liver fibrosis caused by HBV infection in a longitudinal study.

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