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Abstract #2036

BOLD MRI of Activated Human Pancreas

Bozhu Chen1, Jian He, and Zhengyang Zhou

1Radiology, Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing, People's Republic of China

Glucose ingestion activates the pancreatic functions and increases the oxygen consumption, we hypothesized that BOLD MRI could detect the alterations during the glucose challenge. BOLD MRI was performed in 12 volunteers before and after glucose ingestion. A transient but significant decrease in pancreatic T2* values was observed after glucose ingestion. BOLD MRI may serve as a non-invasive tool to detect the activation of human pancreas.

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