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Abstract #2085

Quantification of abdominal subcutaneous and visceral fat by magnetic resonance imaging of the proton at 3T: application to an overfeeding protocol.

Angeline Nemeth1, Hélène Ratiney1, Benjamin Leporq1, Kevin Seyssel2, Bérénice Segrestin3, Pierre-Jean Valette4, Martine Laville3, and Olivier Beuf1

1Univ. Lyon, INSA‐Lyon, Université Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS, Inserm, CREATIS UMR 5220, U1206, F69621, Lyon, France, 2Department of Physiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland, 3Centre de Recherche en Nutrition Humaine Rhône-Alpes (CRNH-RA), Centre Hospitalier Lyon Sud, Pierre-Bénite, Lyon, France, 4Hospices Civils de Lyon, Département d'imagerie digestive, CHU Edouard Herriot, Lyon, France

Overweight and obesity are a major worldwide health problem increasing the risk to develop pathologies such as diabetes and cardiovascular disease. The metabolic risk is modulated by the adiposity distribution and the fatty acid composition. Quantitative MRI to assess the fat volumes and composition is still little used. This study shows, using a single 3D multiple gradient echo sequence, that overfeeding has a significant effect on fat storage in the body with an increase of visceral and subcutaneous abdominal adipose tissues volumes, fat storage in the liver and seems to have an effect on stored fat composition.

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