Meeting Banner
Abstract #2114

Application of Whole-lesion Histogram Analysis of Pharmacokinetic Parameters in Dynamic Contrast-Enhanced MR Imaging of Breast lesions with CAIPIRINHA-Dixon-TWIST-VIBE Technique

Yiqi Hu1, Tao Ai1, Xu Yan2, Dominik Nickel3, and Liming Xia1

1Radiology, Tongji Hospital, Wuhan, People's Republic of China, 2MR Collaboration NE Asia, Siemens Healthcare, 3MR Collaboration, Siemens Healthcare

As the use of neoadjuvant chemotherapy is gradually increased in the treatment of breast cancer, evaluating its therapeutic effect is gaining importance. However, tumors are markedly heterogeneous in cells, micro-environmental factors and vasculature structures, which manifests as radiologic heterogeneity. A few studies have been trying to extract heterogeneity metrics from regions of interest (ROIs) such as by means of histogram analysis. Thus, the aim of our study is to investigate the feasibility of whole-lesion histogram analysis of pharmacokinetic parameters in breast T1-weighted dynamic contrast-enhanced MR imaging (DCE-MRI) for differentiating the malignant from benign breast lesions.

This abstract and the presentation materials are available to members only; a login is required.

Join Here