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Abstract #2116

Advanced Ultrafast Dynamic Contrast Enhanced Breast MRI with Compressed Sensing VIBE

Suzan Vreemann1, Alejandro Rodriguez-Ruiz1, Dominik Nickel2, Marnix Maas1, Nico Karssemeijer1, Elisabeth Weiland2, Berthold Kiefer2, and Ritse Mann1

1Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen, Netherlands, 2MR-Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany

Previous work showed that ultrafast breast DCE-MRI enables assessment of the contrast inflow curve while providing images at diagnostic spatial resolution. However, the slice thickness (~2.5mm) prevented multiplanar reconstructions and therefore did not yield the same morphological information as obtained with conventional T1-weighted series. We evaluate a compressed sensing VIBE sequence (CS-VIBE) for ultrafast breast MRI that enables high spatio-temporal resolution for both dynamic inflow analysis and morphological evaluation. Two reader-studies were conducted to evaluate image quality and lesion morphology assessment. Our results show that CS-VIBE combines the advantages of both high-spatial and high-temporal resolution of clinically available sequences.

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