In order to comparethe diagnosis efficiency of different parameters derived from diffusion kurtosis imaging model in benign and malignant breast lesions, eighty patients were analyzed in this study . DKI data with six b-values and 15 directions were acquired using single-shot SE-EPI sequence. The values of mean kurtosis (MK), axial kurtosis (AK) and radial kurtosis（RK） in malignant lesions group were significantly higher than those in benign lesions groups. The diagnosis efficiency of these parameters were also analyzed. The results showed that DKI-derived parameters can be used to distinguish the malignant lesions and benign lesions, especially AK and MK
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