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Abstract #2125

Perfusion Parameters at Dynamic Contrast-enhanced Breast MR Imaging are Associated with Disease-Specific Survival in Patients with Triple-Negative Breast Cancer

Vivian Youngjean Park1, Eun-Kyung Kim1, Min Jung Kim1, Jung Hyun Yoon1, and Hee Jung Moon1

1Radiology, Yonsei University College of Medicine, Seoul, Korea, Republic of

We investigated the association between perfusion parameters in pretreatment MR imaging and survival outcome. This retrospective study included 61 consecutive patients (median age, 50 years; range, 27-77 years) diagnosed with TNBC who underwent pretreatment DCE breast MR imaging and definitive surgery. The median follow-up time was 46.1 months. Among pretreatment variables, a higher ve value and higher peak enhancement at pretreatment MR imaging were significantly associated with worse disease-specific survival in patients with TNBC. With further validation, these perfusion parameters have the potential to aid in the pretreatment risk stratification of patients with TNBC and in evidence-based clinical decision support.

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