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Abstract #2124

Breast Background Parenchymal Enhancement as a Marker of Breast Cancer Recurrence Risk

Dania Daye1, Dorothy A Sippo1, Elkan F Halpern1, Vishala Mishra1, Constance D Lehman1, and Aditya Bardia2

1Department of Radiology, Massachusetts General Hospital, Boston, MA, United States, 2Department of Medicine, Massachusetts General Hospital, Boston, MA, United States

Emerging studies suggest that imaging features could complement standard pathologic variables in cancer prognostic assessment. Studies on the association of background parenchymal enhancement (BPE) with breast cancer prognosis remain limited. The goal of this study was to investigate the complementary value of breast BPE as a prognostic marker for breast cancer recurrence risk assessment. DCE-MRI images were retrospectively analyzed from 100 women with breast cancer. Oncotype DX score was used as a surrogate for cancer recurrence. Our results suggest that BPE could complement histopathologic factors in predicting breast cancer recurrence risk and could potentially improve breast cancer prognostication.

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