Technical validation of dynamic oxygen–enhanced MRI (OE-MRI) techniques is required for them to become accepted and useful imaging biomarkers. In this work we quantify the impact of using different scanner platforms and protocols on the parameterisation of dynamic single-slice OE-MRI of the lung. Results show that blood in-flow effects consistently provided lower estimates of baseline T1 and higher estimates of maximum change in partial pressure of oxygen, but it does not influence the wash in time estimation. This suggests that sensitivity to variation in ventilation is approximately equivalent using both protocols.
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