Meeting Banner
Abstract #2155

Evaluation of the impact of blood inflow on free-breathing 2D dynamic oxygen-enhanced MRI

Jose L Ulloa1,2, Alexandra R Morgan1, Tony Lacey1, and Geoff JM Parker1,2

1Bioxydyn Ltd, Manchester, United Kingdom, 2School of Health Sciences, The University of Manchester, Manchester, United Kingdom

Technical validation of dynamic oxygen–enhanced MRI (OE-MRI) techniques is required for them to become accepted and useful imaging biomarkers. In this work we quantify the impact of using different scanner platforms and protocols on the parameterisation of dynamic single-slice OE-MRI of the lung. Results show that blood in-flow effects consistently provided lower estimates of baseline T1 and higher estimates of maximum change in partial pressure of oxygen, but it does not influence the wash in time estimation. This suggests that sensitivity to variation in ventilation is approximately equivalent using both protocols.

This abstract and the presentation materials are available to members only; a login is required.

Join Here