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Abstract #2158

k-space based Restoration of Hyperpolarized Xenon-129 MRI

He Deng1, Junshuai Xie1, Huiting Zhang1, Xianping Sun1, and Xin Zhou1

1Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, People's Republic of China

The magnetization of hyperpolarized media (such as Xenon-129, Helium-3 and Carbon-13) is nonrenewable, which makes it difficult to achieve both high signal-to-noise ratio and good spatial resolution in reconstructed MR images. Consequently, a k-space based restoration method is proposed to improve the quality of hyperpolarized MR images in this study, aiming to improve the visual quality of such images. Moreover, a new descriptor is proposed to measure the visual quality of hyperpolarized MR images. Experimental results demonstrated the proposed method is beneficial in visualizing detailed structures in pulmonary images, such as ventilation fine defects.

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